Agencies of the U.S. federal government have invested more than $100 million:

22nd Century Now Free of Restrictive License Agreement with British American Tobacco


Selling snowballs to Eskimos.

Added 01/05/18

Bold and red are my emphasis disbelief.

The FDA together with other agencies of the U.S. government have invested over $100 million in several independent medical studies which have shown the health benefits of the company’s proprietary tobacco cigarettes.

Dr. Dorothy Hatsukami a principal investigator in the trial has publicly indicated that an immediate reduction in consumption of nicotine is “most likely to lead to less harm.

22nd Century Group Inc (NYSEAMERICAN:XXII) Ships 2.4 Million SPECTRUM® Cigarettes for the National Institute on Drug Abuse


Added 01/31/2018

The crimes continue… press release is to settle investors minds, in my opinion.

Cancer Action Network, American Heart Association, American Lung Association, Campaign for Tobacco-Free Kids and the Truth Initiative co-authored a letter to Dr. Gottlieb and the FDA

FDA Remains Firmly Committed to Nicotine Reduction in Cigarettes


Added 02/01/2018

Related via Carl V. Phillips

“There is no reason to believe that lowering the nicotine content of cigarettes will lower their carcinogenicity.”

Are Low-Nicotine Cigarettes Less Likely To Cause Cancer?


Added 02/02/2018

Investors are questioning integrity:

22nd Century – Cutting Through The Smoke And Hype – 75% Downside

Added 03/03/2018

Neal Benowitz himself said: (bold is my emphasis)

CONCLUSIONS

1. Smokers regulate their intake of nicotine to obtain the amount of nicotine that they need to sustain their addiction.

2. Spontaneous brand-switching studies suggest that there is no reduc­tion in smoke intake per cigarette, and that any reductions that are seen in brand switchers depend upon whether or not those individuals also reduce their cigarette consumption.

3. Studies of smokers smoking self-selected brands showed a weak rela­tionship between machine-measured nicotine yield and a smoker’s nicotine, CO, or thiocyanate exposure.

4. Considering the overall exposure data for individuals selecting their own brands, there is little reason to expect that smokers of low-yield ciga­rettes will have a lower risk of disease than those who smoke higher yield cigarettes.

That’s all here in

“Compensatory Smoking of Low Yield Cigarettes”


Added 03/05/2018

Paul also covered this here:

Harm Reduction, Removing the Least Harmful Component


Added 6/21//2018

22nd Century isn’t the “only” one:

Radient Technologies Inc. Files FDA Submission for Reducing Nicotine in Tobacco


Added 7/12/18

From Iowa Attorney General Tom Miller:

Tobacco Product Standard for Nicotine Level of Combusted Cigarettes

Added 7/30/2018:

Minimally or “non-addictive” nicotine

Let me remind you of the accolades of lower nicotine:

Cliff Douglass of the American Cancer Society –  thinks lower nicotine in cigarettes is “Absolutely everything

NCI Director Ned Sharpless says “…good news for treating cancer and preventing cancer

FDA’s Scott Gottlieb claims “Lower nicotine in the same product

Matt Myers of Tobacco-Free Kids says “…to use products that won’t kill them

Basing “minimally or non-addictive” levels of nicotine by lowering cigarette consumption by 1.6 less cigarettes… over two years… is a public health win?  Here’s what they came up with after two years:

238 “non-daily” smokers… what?

over the course of two years...

lowered their smoking by 1.6 cigarettes…

“real-time reporting” and “cigarette butt counts.”

No – to slow progress… is this is what the Food and Drug Administration likes?

One of my favorite subjects – covered here and here

This headline calls it “staggering“.

You can check my math here:

Nondaily Smokers’ Changes in Cigarette Consumption With Very Low-Nicotine-Content Cigarettes

Added 8/09/18:

From a twitter exchange:

Project 2: Strategies for Reducing Nicotine Content in Cigarettes

Added 3/04/2019:

15 to 19 year-olds are being “tested”:

Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers

Added 2/23/2020:

Bold is my emphasis:

Lavery said the FDA “is careful not to reveal its thinking on any potential future actions it may take.”

“But we came away from this meeting with a view that a low-nicotine product standard may be less likely to have scientific support to show that it would be appropriate for the protection of public health.”

22nd Century’s FDA hearing results draw eye-of-beholder responses